Your Name

Long WU

Address: Room 4609, Academic Building, HKUST, Clear Water Bay, Kowloon, Hong Kong.
Email: lwuai@connect.ust.hk

Education

2015-2020PhD in Bioengineering
The Hong Kong University of Science and Technology, Hong Kong
2010-2014MPhil in Computer Science and Technology
Instutite of Computing Technology, University of Chinese Academy of Sciences, Beijing

Working Experience

2021- nowPost-doctoral Fellow
The Hong Kong University of Science and Technology, Hong Kong
2020-2021Post-doctoral Fellow
City University of Hong Kong, Hong Kong

Selected Publications

Hao Chi, Haifeng Chen, Kun He, Long Wu , Bing Yang, Rui-Xiang Sun, Jianyun Liu, Wen-Feng Zeng, Chun-Qing Song, Si-Min He and Meng-Qiu Dong. pNovo+: de novo peptide sequencing using complementary HCD and ETD tandem mass spectra. Journal of Proteome Research, 12(2):615–625, 2012
Shan Lu, Sheng-Bo Fan, Bing Yang, Yu-Xin Li, Jia-Ming Meng, Long Wu , Pin Li, Kun Zhang, Mei- Jun Zhang, Yan Fu, Jincai Luo, Rui-Xiang Sun, Si-Min He and Meng-Qiu Dong. Mapping native disulfide bonds at a proteome scale. Nature Methods, 12(4):329, 2015
Long Wu , Sabine Amon, and Henry Lam. A hybrid retention time alignment algorithm for SWATH-MS data. Proteomics, 16(15-16):2272–2283, 2016
Rui-Xiang Sun, Lan Luo, Long Wu , Rui-Min Wang, Wen-Feng Zeng, Hao Chi, Chao Liu, and Si-Min He. pTop 1.0: a high-accuracy and high-efficiency search engine for intact protein identification. Analytical Chemistry, 88(6):3082–3090, 2016
Hao Chi, Chao Liu, Hao Yang, Wen-Feng Zeng, Long Wu , Wen-Jing Zhou, Rui-Min Wang, Xiu-Nan Niu, Yue-He Ding, Yao Zhang, Zhao-Wei Wang, Zhen-Lin Chen, Rui-Xiang Sun, Tao Liu, Guang-Ming Tan, Meng-Qiu Dong, Ping Xu, Pei-Heng Zhang and Si-Min He. Comprehensive identification of peptides in tandem mass spectra using an efficient open search engine. Nature Biotechnology, 36(11):1059–1061, 2018
Chun Fai Wong, Kar Lun Gallant Chan, Long Wu, Hei Ning Lam, Ping Yao, Tina T. X. Dong, Karl Wah Keung Tsim. A comprehensive proteomics study on edible bird's nest using new monoclonal antibody approach and application in quality control. Journal of Food Composition And Analysis, 66:145-151, 2018
Zhen-Lin Chen, Jia-Ming Meng, Yong Cao, Ji-Li Yin, Run-Qian Fang, Sheng-Bo Fan, Chao Liu, Wen-Feng Zeng, Yue-He Ding, Dan Tan, Long Wu, Wen-Jing Zhou, Hao Chi, Rui-Xiang Sun, Meng-Qiu Dong and Si-Min He. A high-speed search engine pLink 2 with systematic evaluation for proteome-scale identification of cross-linked peptides. Nature Communications 10, 3404 (2019)
Jordy Evan Sulaiman, Lexin Long, Long Wu, Pei-Yuan Qian, Henry Lam, Comparative proteomic investigation of multiple methicillin-resistant Staphylococcus aureus strains generated through adaptive laboratory evolution, iScience, 24(9), 2021
Dominik Madej, Long Wu , and Henry Lam. Common decoy distributions simplify false discovery rate estimation in shotgun proteomics. Journal of Proteome Research, 21(2):339–348, 2022
Long Wu, Ayman Hoque, Henry Lam. Spectroscape: real-time query and visualization of a spectral archive of millions of tandem mass spectra. Under review.

Research Interests

Algorithms
Computational proteomics